Warning: the following info is intended to supplement, not substitute for, the judgment about you're pharmacist. this shouldnot be construed to indicate that use about drug is safe or effective for you. Consult your pharmacist before using this drug.

Methotrexate - oral

(meth-oh-trex-ate)

common brand names: Rheumatrex

Warning: rarely, methotrexate has caused serious (sometimes fatal) side effects. Therefore, this drug should be used only to treat cancer or severe cases of psoriasis or rheumatoid arthritis. Methotrexate has caused birth defects & fetal death. girl should avoid becoming pregnant while taking this medication. Pregnant woman who have psoriasis or rheumatoid arthritis must not use methotrexate. (See also Precautions) If you have kidney problems or excess body water (ascites, pleural effusion), you must be closely monitored & your dose may be adjusted or stopped by your doctor. Infrequently, methotrexate (usually at high dosages) has caused severe (sometimes fatal) bone marrow suppression (decreasing your body's ability to fight infections) and stomach/intestinal disease (e.g., bleeding) when used at the same time as non-steroidal anti- inflammatory drugs (NSAIDs) (e.g., ibuprofen, naproxen). it drug in rare instances may also cause liver problems when it is used for long periods about time. If you are using methotrexate long-term, a liver biopsy is usually recommended. rarely, methotrexate use has resulted at serious (sometimes fatal) lung problems, lung infections (Pneumocystis carinii pneumonia), skin reactions, diarrhea and mouth sores (ulcerative stomatitis). (See also Side Effects) Very infrequently, lumps (tumors/abnormal growths) may appear during methotrexate use. drug must be stopped & treatment may be needed. Consult your doctor immediately if new lumps/growths occur. When used to treat tumors, methotrexate rarely causes side effects due to the rapid destruction about cancer cells (tumor lysis syndrome). Tell your doctor immediately if you experience symptoms such as irregular heartbeat or muscle weakness. Although rare, it drug when used with radiation treatment may increase risk of tissue & bone damage. Discuss risks & benefits about your treatment plan with you're doctor.

Simular Drugs : Methotrexate, Methotrexate, Methotrexate Lpf, Methotrexate Sodium

Methotrexate Usage: Methotrexate is used to treat certain types about cancer or to control severe psoriasis or rheumatoid arthritis. it medication works by interfering with cell growth & by suppressing immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.

Methotrexate can be used also for: it medication has also been used to treat other disorders such as lupus & psoriatic arthritis.

How to use Methotrexate: this is potent tablet. the dose & how often you take this pill is based on your medical condition & response to therapy. there are many different dosing schedules for this medicine (especially for cancer treatment). Therefore, It's very important that you follow youre doctor's instructions carefully. Take it by mouth exactly as directed. since managing psoriasis or rheumatoid arthritis, take this tablet exactly as directed, usually one time a week. it may take up to some months about continued use before the full benefit about this med is seen. do not increase your dose or take it medication more much times with out your doctor's approval. some your condition will not improve any faster & risk of serious side effects may be increased. Unless your healthcare professional instructs you otherwise, drink plenty of fluids while taking this med. it helps youre kidneys to remove the drug from your body & minimize some of side effects. this medication may come with a Patient next info Leaflet. Read it carefully. Ask youre doctor or physician any questions that you may have about this medicine.

Methotrexate side effects: look also the Warning section. Nausea, vomiting, stomach pain, drowsiness or dizziness may occur. If any of these effects persist or worsen, notify your pharmacist or pharmacist promptly. Tell your physician immediately if any of these serious side effects occur: mouth sores, diarrhea, fever, fatigue, persistent sore throat, unusual bleeding or bruising, black stools, skin rash, enlarged glands/lymph nodes, dark urine, bone pain, unusual pain & discoloration of the skin. Tell your doctor immediately if any of these unlikely but serious side effects occur: yellowing of eyes/skin, change in amount of urine, chest pain, dry cough, trouble breathing, calf pain/swelling, vision changes, irregular heartbeat, muscle weakness, mental/mood changes, seizures. Temporary hair loss may occur. Normal hair growth should return after treatment has ended. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your healthcare professional or pharmacist.

Methotrexate Precautions: it medication shouldnot be used if you have certain medical conditions. Before using this medicine, consult you're healthcare professional or pharmacist if you have: liver disease, severe kidney disease, severe lung disease (e.g., pulmonary fibrosis), alcohol use, suppressed immune system, blood cell/bone marrow disorders. Before using this medication, tell youre doctor or pharmacist your medical history, especially of: stomach/intestinal diseases (e.g., peptic ulcer, ulcerative colitis), kidney disease, any active infection (including chickenpox or recent exposure to it), folic acid deficiency, any allergies. this tablet may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Avoid alcoholic beverages. this medication may make you more sensitive to sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use sunscreen & wear protective clothing when outdoors. do not have immunizations/vaccinations without consent of youre physician & avoid contact with person who have recently received oral polio vaccine. Use caution with sharp objects like safety razors or nail cutters & avoid activities such as contact sports to lower chance of getting cut, bruised, or injured. Wash your hands well to prevent the spread of infections. Methotrexate should not be used during pregnancy. it may cause fetal harm. If you become pregnant or think you may be pregnant, inform your pharmacist immediately. Pregnancy must be avoided, therefore males & females should use reliable forms of birth control during & for at least 3 months following finish about methotrexate treatment. Methotrexate passes into breast milk. don't breast-feed while using this drug due to the risk for fetal harm.

Methotrexate drug interactions: this drug shouldnot be used with the following medications because very serious interactions may occur: acitretin, asparaginase, live vaccines, NSAIDs (e.g., ibuprofen, naproxen) with high-dose methotrexate therapy for certain cancers, pyrimethamine. If you are currently using any of these medications, tell your pharmacist or physician before starting methotrexate. Before using it drug, tell youre healthcare professional or pharmacist of all prescription & nonprescription goods you may use, especially of: aspirin/NSAIDs (e.g., ibuprofen, naproxen), another cancer treatments potentially toxic to kidney (e.g., cisplatin), digoxin, leflunomide, other drugs potentially toxic to the liver (e.g., azathioprine, sulfasalazine, retinoids such as isotretinoin), penicillins, phenytoin, probenecid, procarbazine, sulfa medications, theophylline. Certain antibiotics (e.g., chloramphenicol, sulfa, tetracyclines) may interfere with methotrexate blood tests (increase methotrexate blood levels due to protein-binding displacement). Make sure laboratory personnel & some your healthcare professionals know you are using any of these types of antibiotics. don't start or stop any medicine without physician or healthcare professional approval.

Methotrexate Overdose: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms about overdose may include severe nausea & vomiting, & bloody stools.

Methotrexate special notes: don't share it medication with others. Laboratory and/or medical tests (e.g., CBC, liver and kidney function tests) should be performed periodically to monitor your progress or cash for side effects. Consult your pharmacist for more details.

If you missed Methotrexate dose: It's important to use each dose at the scheduled clock. If you miss dose, contact your doctor to establish a new dosing schedule. do not 'double-up' dose to catch up.

Methotrexate Storage: Store it medication at room temperature between 59 to 86 degrees F (15 to 30 degrees C) away from light & moisture. do not store in bathroom. Keep every medicines away from child and pets.

Medical alert: your condition can cause complications at medical emergency.

Active Ingredients : Methotrexate